{"id":16412,"date":"2022-02-16T12:00:21","date_gmt":"2022-02-16T17:00:21","guid":{"rendered":"https:\/\/www.veriheal.com\/blog\/?p=16412"},"modified":"2023-11-01T13:55:19","modified_gmt":"2023-11-01T17:55:19","slug":"what-does-research-say-about-psychedelic-therapy-for-autism","status":"publish","type":"post","link":"https:\/\/www.veriheal.com\/blog\/what-does-research-say-about-psychedelic-therapy-for-autism\/","title":{"rendered":"What Does Research Say About Psychedelic Therapy for Autism?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">In an account of his life with autism featured in <\/span><a href=\"https:\/\/www.medicalnewstoday.com\/articles\/325239#Growing-up-with-autism\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Medical News Today\u2019s Through My Eyes series<\/span><\/a><span style=\"font-weight: 400;\">, Jonathan Rowland explains that \u201cthere are a number of preconceptions\u201d about how one is \u201csupposed to look, as well as what an autistic person is and is not capable of\u201d\u2014which is only the beginning of the challenges one may experience with autism spectrum disorder (ASD). <\/span><a href=\"https:\/\/www.veriheal.com\/blog\/cbdv-research-shows-a-strong-potential-for-autism-spectrum-disorder\/\"><span style=\"font-weight: 400;\">Research into cannabis for ASD has shown promise<\/span><\/a><span style=\"font-weight: 400;\">, and researchers are now finding <\/span><a href=\"https:\/\/www.veriheal.com\/blog\/a-quick-guide-to-the-many-types-of-psychedelic-therapy\/\"><span style=\"font-weight: 400;\">psychedelics<\/span><\/a><span style=\"font-weight: 400;\"> to have the potential to benefit autistic people.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Filter collaborated with Narcotica in a <\/span><a href=\"https:\/\/narcocast.com\/episode-57-autism-acid-and-the-altered-brain-with-aaron-orsini-and-justine-lee\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">podcast<\/span><\/a><span style=\"font-weight: 400;\"> in order to understand the experiences of autistic people who have benefited from psychedelics. Filter reported that MDMA and psilocybin have both \u201cbeen deemed \u2018breakthrough therapies\u2019 by the Food and Drug Administration and appear poised for approval, <\/span><a href=\"https:\/\/www.nytimes.com\/2021\/05\/03\/health\/mdma-approval.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">if no sooner than 2023<\/span><\/a><span style=\"font-weight: 400;\">.\u201d\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Considering the many surfacing studies on the efficacy of psychedelic therapies, many researchers have turned their attention to \u201crelieving symptoms of autism spectrum disorder (ASD)\u201d through these psychedelics, according to Filter. Before we get into what this means, let\u2019s take a look at the condition itself.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">An Overview of Autism Spectrum Disorder<\/span><\/h2>\n<p><a href=\"https:\/\/www.veriheal.com\/conditions\/autism-spectrum-disorder\/\"><span style=\"font-weight: 400;\">ASD<\/span><\/a><span style=\"font-weight: 400;\"> is a broad term used to categorize individuals who have challenges with social skills as well as those who have repetitive behaviors, speech, and challenging nonverbal communication. <\/span><a href=\"https:\/\/www.cdc.gov\/ncbddd\/autism\/facts.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">The Centers for Disease Control and Prevention (CDC)<\/span><\/a><span style=\"font-weight: 400;\"> explains that there is nothing visible that sets those with ASD apart from others aside from their challenges with communication, interaction, behavior, and learning.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">So, how does ASD present itself? It is normally diagnosed in childhood. People with the condition might: not show interest in objects, have trouble relating to others and having an interest in them, avoid eye contact, want to be alone, have trouble understanding feelings or talking about their own, appear unaware when others are talking to them, be unsure how to talk to others, repeat phrases\/words and actions, struggle to adapt to changes in routine, and have unusual reactions to stimulus like touch and smell. Early behavioral intervention is still key to the best long-term outcomes.\u00a0 Many ASD children benefit from therapies that focus on social conversational skills, dealing with sensory stimuli, and identifying their emotions and the emotions of those around them.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Psychedelic Therapy for ASD Social Anxiety<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Filter reported that Nova Mentis Life Science Corp <\/span><a href=\"https:\/\/psilocybinalpha.com\/news\/nova-mentis-psilocybin-approved-for-shipment-to-italy\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">will be conducting an observational study<\/span><\/a><span style=\"font-weight: 400;\"> \u201con the microbiome and genetics of patients with ASD and Fragile X syndrome.\u201d Part of the study is focused on serotonin signaling\u2014the chemical in the brain most associated with psychedelic effects\u2014which is apparently due to the fact that the company wants to \u201cilluminate the neural underpinnings of social anxiety relating to ASD.\u201d\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, the Multidisciplinary Association for Psychedelic Studies (MAPS) has been the only organization to conduct and complete a clinical trial on MDMA\u2019s ability to treat social anxiety in autistic adults. While the <\/span><a href=\"https:\/\/link.springer.com\/article\/10.1007\/s00213-018-5010-9\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">2018 study<\/span><\/a><span style=\"font-weight: 400;\"> was only conducted on a small scale, it \u201cdemonstrated rapid and durable improvement in social anxiety symptoms.\u201d Berra Yazar-Klosinski, the study\u2019s author, told Filter that despite the small study size, the \u201cresults had a large effect size, which means that it\u2019s a strong signal that we might be able to alleviate the social anxiety symptoms that they were suffering from.\u201d\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Berra also explained that they followed up with the participants and found that \u201cmany of the participants had completely transformed lives after the study.\u201d Unfortunately, it will be a while before a larger scale study can be conducted in order to assess the efficacy of MDMA for autism since the FDA will need to approve such studies\u2014and the substance is still widely illegal.\u00a0 Currently, the only active autism and psychedelic trial study that is registered with the National Institutes of Health is a <\/span><a href=\"https:\/\/www.clinicaltrials.gov\/ct2\/show\/NCT04053036\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\"> being conducted by the University of Chicago.<\/span><\/p>\n<p><a href=\"https:\/\/news.sky.com\/story\/lsd-breakthrough-could-enable-treatment-for-autism-and-social-anxiety-research-finds-12200193\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Sky News<\/span><\/a><span style=\"font-weight: 400;\"> reported on a study led by researchers at McGill University in Canada that found potential in using LSD to treat social anxiety and increase socialization in those with autism. The study suggests that the mechanism which enables LSD \u201ccould be used to treat anxiety and autism spectrum disorder,\u201d and that the combined activation of serotonin receptors and AMPHA receptors by the drug leads to increased social interaction. However, the study was conducted on mice, so the results may not be reflective of human reactions and are yet to be seen.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">The Need for More Clinical Trials<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Those on the autism spectrum can live beautiful, robust lives, but some of the symptoms that come with the condition\u2014like debilitating social anxiety\u2014can make daily functions difficult. Based on the available studies but subject to their limitations, psychedelics offer the potential to induce more positive moods, improve inclination to interact with others, improve speech, enhance emotional responsiveness, and reduce the occurrence of obsessive and repetitive behavior.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There are plenty of anecdotal reports to echo these effects, but the jury is still out on when clinical trials for the therapeutic efficacy of such substances will be allowed or conclusive. It also appears that LSD, <\/span><a href=\"https:\/\/www.veriheal.com\/blog\/researchers-weigh-in-on-the-hype-about-mdma-therapy\/\"><span style=\"font-weight: 400;\">MDMA<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.veriheal.com\/blog\/discover-the-many-types-of-psilocybin-magic-mushrooms\/\"><span style=\"font-weight: 400;\">psilocybin<\/span><\/a><span style=\"font-weight: 400;\"> will be receiving the most attention in terms of understanding psychedelics as a potential treatment for ASD. Consuming psychedelics is still illegal and should not be used to self-medicate unless you are in an environment where psychedelic-assisted therapy is allowed under the guidance of a professional.\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><i><span style=\"font-weight: 400;\">Veriheal does not support illegally consuming therapeutic substances such as psychedelics but acknowledges that it transpires because of the current illicit status, which we strive to change by advocating for research, legal access, and responsible consumption. Always consult a physician before attempting alternative therapies.<\/span><\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In an account of his life with autism featured in Medical News Today\u2019s Through My Eyes series, Jonathan Rowland explains that \u201cthere are a number of preconceptions\u201d about how one is \u201csupposed to look, as well as what an autistic person is and is not capable of\u201d\u2014which is only the beginning of the challenges one&#8230;<\/p>\n","protected":false},"author":49,"featured_media":19171,"parent":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[259],"tags":[7282,2780,8099,8098,1379,13011],"class_list":["post-16412","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","tag-asd","tag-autism","tag-medical-psychedelics","tag-psychedelic-therapy","tag-psychedelics","tag-social-anxiety"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.1 (Yoast SEO v26.1.1) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cannabis Central<\/title>\n<meta name=\"description\" content=\"Numerous emerging studies support the therapeutic potential of psychedelics to treat symptoms like social anxiety in adults with autism spectrum disorder.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, 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