{"id":16602,"date":"2022-03-31T15:30:32","date_gmt":"2022-03-31T19:30:32","guid":{"rendered":"https:\/\/www.veriheal.com\/blog\/?p=16602"},"modified":"2023-11-01T13:56:04","modified_gmt":"2023-11-01T17:56:04","slug":"lets-explore-the-cbc-cannabinoid-and-its-therapeutic-benefits","status":"publish","type":"post","link":"https:\/\/www.veriheal.com\/blog\/lets-explore-the-cbc-cannabinoid-and-its-therapeutic-benefits\/","title":{"rendered":"Let&#8217;s Explore the Cannabinoid CBC and Its Therapeutic Benefits"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">While tetrahydrocannabinol (<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/uncovering-thc-the-cannabis-plants-most-famous-cannabinoid\/\"><span style=\"font-weight: 400;\">THC<\/span><\/a><span style=\"font-weight: 400;\">) and cannabidiol (<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/veriheals-complete-guide-to-cbd-heres-everything-you-need-to-know\/\"><span style=\"font-weight: 400;\">CBD<\/span><\/a><span style=\"font-weight: 400;\">) will likely remain public favorites, other cannabinoids have the potential to outperform their currently expected therapeutic potential. Cannabichromene, or CBC, is explained to be a powerful and non-psychoactive cannabinoid compound. <\/span><a href=\"https:\/\/www.crescolabs.com\/cannabinoids\/cbc\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Cresco Labs<\/span><\/a><span style=\"font-weight: 400;\"> reports that CBC has significant capabilities in terms of therapeutic potential, but will CBC be the cannabinoid to outperform CBD? Let\u2019s find out.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Cannabinoids are the organic compounds that naturally occur in the cannabis plant as well as have the ability to bind to the endocannabinoid system receptors, plus others, in order to deliver their benefits. While most of the cannabinoid varieties identified are available in lower quantities when compared to THC and CBD, <\/span><a href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/cannabichromene\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">ScienceDirect<\/span><\/a><span style=\"font-weight: 400;\"> explains that CBC can be \u201cone of the most abundant non-psychotropic CBs found in strains or varieties of cannabis.\u201d The fact that CBC is non-psychotropic means that consumers will not have to expect the effects associated with being intoxicated from cannabis, particularly from the cannabinoid THC.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">CBC has the ability to deliver effects through the activation of our CB2 receptors, PPAR and TRPA1 receptors, and multiple ways of increasing endocannabinoid tone. However, since it does not activate the CB1 receptors, Cresco Labs recommends combining CBC with THC to unlock more potential if desired. Despite this instance, it is recommended that consumers try to consume cannabis products that are broad- and full-spectrum in order to benefit from the entourage effect.<\/span><\/p>\n<h2><strong>CBC\u2019s Therapeutic Effects<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">Cresco Labs explains that CBC has shown to be effective in the treatment of \u201ca variety of symptoms and conditions\u201d- much like many other cannabinoids. They go on to list conditions for which CBC is especially effective, which included <\/span><a href=\"https:\/\/www.veriheal.com\/conditions\/inflammatory-bowel-disease\/\"><span style=\"font-weight: 400;\">IBS<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.veriheal.com\/conditions\/crohns-disease\/\"><span style=\"font-weight: 400;\">Crohn\u2019s disease<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.veriheal.com\/conditions\/neuropathy\/\"><span style=\"font-weight: 400;\">neuropathy<\/span><\/a><span style=\"font-weight: 400;\">, and chronic postoperative pain but can also include <\/span><a href=\"https:\/\/www.veriheal.com\/conditions\/cancer\/\"><span style=\"font-weight: 400;\">cancer<\/span><\/a><span style=\"font-weight: 400;\">, neurological diseases, <\/span><a href=\"https:\/\/www.veriheal.com\/conditions\/acne\/\"><span style=\"font-weight: 400;\">acne<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.veriheal.com\/conditions\/depression\/\"><span style=\"font-weight: 400;\">depression<\/span><\/a><span style=\"font-weight: 400;\">, and pretty much any condition marked by <\/span><a href=\"https:\/\/www.veriheal.com\/conditions\/chronic-pain\/\"><span style=\"font-weight: 400;\">pain<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.veriheal.com\/conditions\/inflammation\/\"><span style=\"font-weight: 400;\">inflammation<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3><strong>Acne<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">An in-vitro <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27094344\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\"> published in 2016 found that CBC, in addition to <a href=\"https:\/\/www.veriheal.com\/blog\/cbdv-a-comprehensive-guide-exploring-the-extensive-healing-potential-of-this-rare-cannabinoid\/\">CBDV<\/a> and especially THCV, had powerful anti-inflammatory properties which were accompanied by a strong inclination toward <\/span><a href=\"https:\/\/www.veriheal.com\/blog\/the-bioavailability-of-cannabis-through-various-delivery-methods\/\"><span style=\"font-weight: 400;\">topical applications<\/span><\/a><span style=\"font-weight: 400;\"> with especially significant anti-acne properties. The team explains that while CBD also has anti-inflammatory properties, the CBC appears to be the stronger contender, especially if your concern is acne. Gabe Kennedy, the co-founder of Plant People, told the <\/span><a href=\"https:\/\/www.thezoereport.com\/p\/cbc-cannabinoids-benefits-are-actually-very-different-from-cbd-19212842\"><span style=\"font-weight: 400;\">media<\/span><\/a><span style=\"font-weight: 400;\"> that they choose to \u201cinclude higher levels of CBC\u201d for their skincare products based on the cannabinoid\u2019s superior anti-inflammatory properties.\u00a0<\/span><\/p>\n<h3><strong>Cancer<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">CBC was found to have the potential to inhibit inflammation in cancer patients, but more than that, it was found to have the <\/span><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/jphp.12082\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">potential to inhibit tumor growth<\/span><\/a><span style=\"font-weight: 400;\"> in skin, breast, prostate, and colon cancer cell models (<\/span><a href=\"#references\"><span style=\"font-weight: 400;\">11<\/span><\/a><span style=\"font-weight: 400;\">) (<\/span><a href=\"#references\"><span style=\"font-weight: 400;\">12<\/span><\/a><span style=\"font-weight: 400;\">). The cannabinoid <\/span><a href=\"https:\/\/jpet.aspetjournals.org\/content\/318\/3\/1375.long\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">shows great promise as a chemopreventive agent <\/span><\/a><span style=\"font-weight: 400;\">with the second-most potent tumor inhibitor in terms of the various cannabinoids. However, more research is necessary to confirm whether CBC can be used to treat cancer as opposed to merely slowing progression in early models.\u00a0<\/span><\/p>\n<h3><strong>Depression<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">CBC has been <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20332000\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">found to perform effectively as an antidepressant<\/span><\/a><span style=\"font-weight: 400;\"> on its own in animal studies. Effective means of alleviating depression are increasingly important as the number of depressed individuals continues to grow as the years go by. Fortunately, <\/span><a href=\"https:\/\/www.veriheal.com\/blog\/using-cannabis-to-treat-symptoms-of-depression\/\"><span style=\"font-weight: 400;\">cannabis is a friend for depressed<\/span><\/a><span style=\"font-weight: 400;\"> individuals in many circumstances.\u00a0<\/span><\/p>\n<h3><strong>Pain and Inflammation<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">A <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20942863\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">2011 study<\/span><\/a><span style=\"font-weight: 400;\"> found that CBC was effective in blocking pain as well as inhibiting inflammation when tested on rats. <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22300105\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">CBC&#8217;s ability to inflammation<\/span><\/a><span style=\"font-weight: 400;\"> and pain is not exactly a new discovery, but the significant thing to note here is that the CBC protects against intestinal inflammation on its own through ways unknown, not via CB or TRP receptors. It did increase the number of cannabinoid and TRP receptors in the rat gut but did not reduce intestinal transit time, requiring further investigation.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Pain and inflammation are major symptoms of many medical conditions. Having more botanical options to alleviate the pain and inflammation is not only necessary for improved quality of life, but it is also necessary to remove any risk of addiction and negative health effects from pharmaceuticals commonly administered like opioids.\u00a0<\/span><\/p>\n<h3><strong>Promotion of Brain Homeostasis<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">When CBC was studied on mice in a 2013 study, the researchers found that CBC promoted the growth of brain cells and maintenance of homeostasis in the brain through its <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23941747\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">positive effects on the Neural Stem Progenitor Cells (NSPCs)<\/span><\/a><span style=\"font-weight: 400;\">. Homeostasis of the brain refers to a stable and balanced state within the brain. We can use cannabis to promote this thanks to the <\/span><a href=\"https:\/\/www.veriheal.com\/blog\/cannabinoids-and-the-endocannabinoid-system-a-match-made-in-heaven\/\"><span style=\"font-weight: 400;\">endocannabinoid system<\/span><\/a><span style=\"font-weight: 400;\"> and the many receptors located all over the body.\u00a0<\/span><\/p>\n<h2><strong>More on CBC<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">ScienceDirect explains that CBC represents ~0.3% of \u201cconstitutes from confiscated cannabis\u201d and that \u201cit is important to note that varieties and preparations exist in the commercial and medical markets with significantly high content.\u201d This means CBC is a relatively more common minor cannabinoid. They go on to explain that strains that are rich in CBC are the \u201cresult of selecting for the inheritance of a recessive gene\u201d which happens through extensive<\/span><a href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/cannabichromene\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\"> cross-breeding<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ethan Russo and Jahan Marcu also <\/span><a href=\"https:\/\/www.veriheal.com\/blog\/wp-content\/uploads\/2021\/08\/The-Usual-Suspects-and-a-Few-Promising-Leads.pdf\"><span style=\"font-weight: 400;\">found<\/span><\/a><span style=\"font-weight: 400;\"> that they were able to locate \u201cCBC or CBC-like derivatives,\u201d from a plant known as <\/span><a href=\"https:\/\/naturelib.net\/plantae\/rhododendron-anthopogonoides\/\" target=\"_blank\" rel=\"noopener\"><i><span style=\"font-weight: 400;\">Rhododendron anthopogonoides<\/span><\/i><\/a> <span style=\"font-weight: 400;\">which is a small, erect shrub with pretty flowers. At the time of conducting their research, the plant and its derivatives were not \u201clisted under the list of scheduled drugs by the DEA,\u201d despite the benefits one may receive from the CBC-like derivatives of the plant.\u00a0<\/span><\/p>\n<h2><strong>Strains High in CBC<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">Cannabis strains need to be selected and cross-bred based on genetics in order to produce strains with a high quantity of CBC. It appears that there are not many well-known strains available specifically pertaining to CBC, however, there is one that we know of for sure. This strain is made of a combination of Headband, OG Kush, and Sour Diesel. The strain has rather suitably been dubbed the Three Kings. There are some other suggestions that include <\/span><a href=\"https:\/\/www.veriheal.com\/blog\/strains\/landrace\/\"><span style=\"font-weight: 400;\">landrace strains<\/span><\/a> <span style=\"font-weight: 400;\">from India as well as Purple Cadillac, Sour Tsunami, and Purple Candy. However, we recommended that consumers looking for CBC choose products based on their cannabinoid contents on the label as well as looking at the product\u2019s <\/span><a href=\"https:\/\/www.veriheal.com\/blog\/all-about-cannabis-third-party-testing-and-certificates-of-analysis\/\"><span style=\"font-weight: 400;\">certificate of analysis<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span id=\"references\" style=\"font-weight: 400;\">Of course, more research is needed to better understand the spectrum of risks and benefits of CBD and CBC. Always exercise caution when it comes to cannabis therapy and consult your medical physician, <\/span><a href=\"https:\/\/www.veriheal.com\/\"><span style=\"font-weight: 400;\">or ours<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>While tetrahydrocannabinol (THC) and cannabidiol (CBD) will likely remain public favorites, other cannabinoids have the potential to outperform their currently expected therapeutic potential. Cannabichromene, or CBC, is explained to be a powerful and non-psychoactive cannabinoid compound. Cresco Labs reports that CBC has significant capabilities in terms of therapeutic potential, but will CBC be the cannabinoid&#8230;<\/p>\n","protected":false},"author":49,"featured_media":16867,"parent":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[259],"tags":[12804,12802,12801,12803,64,2261,4581,4583],"class_list":["post-16602","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","tag-acne","tag-cannabichromene","tag-cbc","tag-chrohns-disease","tag-chronic-pain","tag-depression","tag-ibd","tag-ibs"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.1 (Yoast SEO v26.1.1) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cannabis Central<\/title>\n<meta name=\"description\" content=\"Thanks to increasing research on cannabis, another new cannabinoid has been discovered. Check out CBC and its therapeutic benefits.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.veriheal.com\/blog\/lets-explore-the-cbc-cannabinoid-and-its-therapeutic-benefits\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Let&#039;s Explore the Cannabinoid CBC and Its Therapeutic Benefits\" \/>\n<meta property=\"og:description\" content=\"Thanks to increasing research on cannabis, another new cannabinoid has been discovered. Check out CBC and its therapeutic benefits.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.veriheal.com\/blog\/lets-explore-the-cbc-cannabinoid-and-its-therapeutic-benefits\/\" \/>\n<meta property=\"og:site_name\" content=\"Cannabis Central\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/veriheal\" \/>\n<meta property=\"article:published_time\" content=\"2022-03-31T19:30:32+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-11-01T17:56:04+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.veriheal.com\/blog\/wp-content\/uploads\/2021\/07\/Lets-Explore-the-CBC-Cannabinoid-and-its-Therapeutic-Benefits.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1800\" \/>\n\t<meta property=\"og:image:height\" content=\"1200\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Chane Leigh\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:description\" content=\"Thanks to increasing research on cannabis, another new cannabinoid has been discovered. 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