{"id":23477,"date":"2022-09-12T08:00:11","date_gmt":"2022-09-12T12:00:11","guid":{"rendered":"https:\/\/www.veriheal.com\/blog\/?p=23477"},"modified":"2025-02-25T12:50:33","modified_gmt":"2025-02-25T17:50:33","slug":"study-cannabis-consumers-are-less-likely-to-be-diagnosed-with-liver-cancer","status":"publish","type":"post","link":"https:\/\/www.veriheal.com\/blog\/study-cannabis-consumers-are-less-likely-to-be-diagnosed-with-liver-cancer\/","title":{"rendered":"Study: Cannabis Consumers Are Less Likely to Be Diagnosed With Liver Cancer"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Cannabis has been proving its therapeutic potential as a treatment option for many diseases and conditions. However, what is often neglected when thinking about cannabis and its benefits is the fact that it can protect people from so much. Joining amongst the ranks of protecting your skin from free radicals and protecting and improving neuroplasticity, as a condition which cannabis can assist with protecting you from is liver cancer, specifically hepatocellular carcinoma. Not only will cannabis assist with lowering your odds of presenting with this cancer, but it also shows promise as a life-saving treatment option.\u00a0<\/span><\/p>\n<h2><b>Studying Cannabis and Liver Cancer<\/b><\/h2>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35651376\/\"><span style=\"font-weight: 400;\">Data published in the scientific journal <\/span><i><span style=\"font-weight: 400;\">Cureus<\/span><\/i><\/a><span style=\"font-weight: 400;\"> has found that adults who have a recent history of cannabis consumption are twice less likely to present with hepatocellular carcinoma (HCC)- which is the most common type of live cancer- when compared to adults who have never consumed cannabis. Ahmed ElTelbany and colleagues reported that those who have a recent history of cannabis use were \u201c55 percent less likely to have HCC compared to patients without cannabis use.\u201d ElTelbany et al used a total of 101, 231, 036 participants in their study, out of which 996, 290 (1%) patients had a diagnosis of cannabis abuse while remaining 99% had not been diagnosed with cannabis abuse- making this portion the control group.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">ElTelbany and colleagues used multivariable logistic regression, adjusted for potential confounders, and found that \u201cpatients with cannabis abuse were 55% less likely to have HCC\u2026\u201d The researchers concluded by stating that \u201cTo the best of our knowledge, this is the first and largest population-based cross-sectional study of hospitalized patients to explore the association between cannabis use and HCC. \u2026 Due to the cross-sectional structure of our study, we are unable to draw direct causation effects. Hence, we suggest prospective clinical studies to further understand the mechanism by which various active ingredients, particularly CBD in cannabis, may possibly regulate hepatocellular carcinoma development.\u201d\u00a0<\/span><\/p>\n<h2><b>Hepatocellular Carcinoma\u00a0<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Hepatocellular carcinoma (HCC) is a common liver cancer which is more likely to occur in people who have dealt with chronic liver-based disorders such as cirrhosis, <\/span><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/hepatocellular-carcinoma\/cdc-20354552#:~:text=Hepatocellular%20carcinoma%20(HCC)%20is%20the,B%20or%20hepatitis%20C%20infection\"><span style=\"font-weight: 400;\">explains the Mayo Clinic<\/span><\/a><span style=\"font-weight: 400;\">. However, Mayo Clinic explains that this type of liver cancer is also commonly found in people who consume large amounts of alcohol and who have accumulated fat in the liver. <\/span><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/liver-cancer\/symptoms-causes\/syc-20353659\"><span style=\"font-weight: 400;\">They go on to explain that<\/span><\/a><span style=\"font-weight: 400;\"> HCC begins in the main liver cell known as hepatocyte but that \u201ccancer that spreads to the liver is more common than cancer that begins in the liver cells.\u201d Much like other cancers, HCC is named after the location of its origin.\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While most people won\u2019t show any signs or have any symptoms during the early stages of HCC, when they do start appearing, they include losing weight without trying, loss of appetite, upper abdominal pain, nausea, vomiting, fatigue, weakness, abdominal swelling, yellow discoloration of the skin and teeth (jaundice), white \u2018chalky\u2019 stool, according to the Mayo Clinic. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Risk factors associated with this cancer include having a chronic infection with hepatitis B virus or hepatitis C virus, having dealt with cirrhosis, diabetes, inherited liver diseases such as hemochromatosis, exposure to aflatoxins, drinking too much alcohol, etc. While doctors may be able to identify where the liver cancer came from, there are still circumstances where the cause of the liver cancer remains unknown.\u00a0\u00a0\u00a0\u00a0<\/span><\/p>\n<h2><b>The Anti-Tumoral Action of Cannabis on HCC<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">While ElTelbany and colleagues research concerning the likelihood of cannabis consumers presenting with HCC was only published recently, there are those who have looked to cannabis as a potential means of dealing with HCC. For example, researchers <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3131949\/\"><span style=\"font-weight: 400;\">Vara, Salazar, Olea-Herrero and colleagues found<\/span><\/a><span style=\"font-weight: 400;\"> that cannabis, particularly tetrahydrocannabinol (THC) and a specific CB2 receptor known as JWH-015 \u201creduced the viability of human HCC cell lines.\u201d <\/span><\/p>\n<p><span style=\"font-weight: 400;\">The researchers go on to explain that THC can trigger human glioma (a type of tumor in the brain or spine) cell death\u201d- which is what led the team to consider the cannabinoid for HCC. They state that their research shows \u201cthat the natural cannabinoid \u03949-THC and the CB2 receptor-selective agonist JWH-015 inhibit HCC cell growth via stimulation of autophagy. In other words, THC was found to promote anti-tumoral action in the body, thereby reducing chances, or rates, of the HCC becoming malignant (becoming invasive, aggressive and deadly).\u00a0<\/span><\/p>\n<h2><b>Cannabis Oil for Liver Cancer<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Meanwhile, <\/span><a href=\"https:\/\/www.rug.nl\/about-ug\/latest-news\/news\/archief2021\/nieuwsberichten\/umcg-studies-cannabis-oil-for-liver-cancer-patients-with-no-further-treatment-options?lang=en#:~:text=Although%20laboratory%20research%20shows%20that,research%20has%20been%20carried%20out.\"><span style=\"font-weight: 400;\">researchers from the University Medical Center Groningen (UMCG) investigated<\/span><\/a><span style=\"font-weight: 400;\"> the use of cannabis oil for liver cancer patients who have no further treatment options. The university reports that their research began as the result of two cases where \u201cpatients who have exhausted all other treatment options\u201d turned to cannabis oil and their liver tumors began to shrink and eventually \u201ccompletely disappeared.\u201d While their research has not been published yet, they plan to involve 20 patients and they plan to carry out this research in order to help those who have \u2018supportive care\u2019 as their only option- at least until they try the cannabis oil.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">HCC claims the lives of almost 32, 000 people every year in America alone. <\/span><span style=\"font-weight: 400;\">Ailor explains that<\/span><span style=\"font-weight: 400;\"> the amount of people who die from HCC has more than tripled since 1980 as a result of the risse in the hepatitis B &#8211; and C- viruses. They go on to explain that the deaths caused from HCC are increasing much more than that of the deaths caused by any other cancer and that this large mortality rate is largely due to the fact that people are diagnosed during late-stages- which are often deemed too late.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While ElTelbany and colleagues found that frequent cannabis consumers have much better chances of avoiding the HCC, it remains unclear whether any of those cannabis consumers in the study actually had any of the risks which would make them susceptible to HCC. Still, the chances are lower than those who do not consume cannabis. For those who are at risk of HCC or who have already been diagnosed with HCC, consider cannabis oil as a treatment option- you have nothing to lose but everything to gain from making the decision to turn to cannabis.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cannabis has been proving its therapeutic potential as a treatment option for many diseases and conditions. However, what is often neglected when thinking about cannabis and its benefits is the fact that it can protect people from so much. Joining amongst the ranks of protecting your skin from free radicals and protecting and improving neuroplasticity,&#8230;<\/p>\n","protected":false},"author":49,"featured_media":24232,"parent":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[255,259],"tags":[2537,12882,1876,2417,13442],"class_list":["post-23477","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-research","tag-cancer","tag-cannabis-for-cancer","tag-cannabis-research","tag-cannabis-study","tag-liver-cancer"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.1 (Yoast SEO v26.1.1) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cannabis Central<\/title>\n<meta name=\"description\" content=\"A new study with a hefty sample size discovered that cannabis consumers have a lower chance of contracting liver 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