{"id":26383,"date":"2024-11-19T08:00:29","date_gmt":"2024-11-19T13:00:29","guid":{"rendered":"https:\/\/www.veriheal.com\/blog\/?p=26383"},"modified":"2026-04-06T07:23:33","modified_gmt":"2026-04-06T11:23:33","slug":"can-you-absorb-thc-through-skin","status":"publish","type":"post","link":"https:\/\/www.veriheal.com\/blog\/can-you-absorb-thc-through-skin\/","title":{"rendered":"Can THC Be Absorbed Through the Skin?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">For those who suffer from muscle pain, chronic pain, or joint pain, cannabis topicals can be a game-changer &#8212; but how exactly do they work?\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Let\u2019s explore whether it\u2019s possible for THC in any of its forms to be absorbed through the skin, and if THC topicals can be detected on\u00a0<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/discover-how-long-thc-can-be-detected-in-your-system\/\"><span style=\"font-weight: 400;\">drug tests<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h2><b>Top Ways to Consume THC<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">There are limited ways for THC to enter your system. Cannabinoids like\u00a0<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/uncovering-thc-the-cannabis-plants-most-famous-cannabinoid\/\"><span style=\"font-weight: 400;\">delta-9-tetrahydrocannabinol (THC)<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/cbd\/\"><span style=\"font-weight: 400;\">cannabidiol (CBD)<\/span><\/a><span style=\"font-weight: 400;\">, and\u00a0<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/exploring-cbn-the-sleepy-cannabinoid\/\"><span style=\"font-weight: 400;\">cannabinol (CBN)<\/span><\/a><span style=\"font-weight: 400;\">\u00a0are processed by the body\u2019s\u00a0<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/cannabinoids-and-the-endocannabinoid-system-a-match-made-in-heaven\/\"><span style=\"font-weight: 400;\">endocannabinoid system (ECS)<\/span><\/a><span style=\"font-weight: 400;\">, interacting with cannabinoid receptors.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">We also now know that there are many other receptors and molecules involved that are part of what\u2019s called &#8220;<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/piecing-together-the-endocannabinoidome-charting-the-next-frontier\/\"><span style=\"font-weight: 400;\">the endocannabinoidome<\/span><\/a>&#8221; <span style=\"font-weight: 400;\">(eCBome), which includes lesser-known endocannabinoid-like molecules (PEA, etc.) and their target receptors like dopamine, PPAR, TRP, and serotonin receptors to enhance their effects.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">THC has pain-relieving (analgesic) properties and produces the intoxicating, psychoactive effects often associated with cannabis consumption. It\u2019s also the culprit behind some of the\u00a0<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/research-suggests-that-high-potency-thc-products-arent-for-everyone\/\"><span style=\"font-weight: 400;\">negative, dose-dependent side effects<\/span><\/a><span style=\"font-weight: 400;\">\u00a0of cannabis, such as paranoia.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Meanwhile, CBD is known for its relaxing effects, anti-anxiety and antidepressant actions, anti-inflammatory properties, and for being a powerful antioxidant. CBD works without causing a high as THC does.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The\u00a0<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/the-bioavailability-of-cannabis-through-various-delivery-methods\/\"><span style=\"font-weight: 400;\">bioavailability<\/span><\/a><span style=\"font-weight: 400;\">\u00a0(i.e., ability to be absorbed into the body) of cannabis can vary greatly depending on the\u00a0<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/how-to-enjoy-the-benefits-of-cannabis-without-smoking\/\"><span style=\"font-weight: 400;\">different delivery methods used<\/span><\/a><span style=\"font-weight: 400;\">. Let\u2019s briefly explore some common consumption methods and how they affect the bioavailability of cannabinoids like THC.<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Inhalation (Smoking and Vaping)<\/strong>: Inhalation includes vaping or dabbing\u00a0<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/the-ultimate-guide-to-cannabis-concentrates\/\"><span style=\"font-weight: 400;\">concentrates<\/span><\/a><span style=\"font-weight: 400;\">\u00a0and smoking or <\/span><a href=\"https:\/\/www.veriheal.com\/blog\/dry-herb-vaporizing-a-healthier-alternative-to-smoking-cannabis\/\"><span style=\"font-weight: 400;\">vaping dried cannabis flower<\/span><\/a><span style=\"font-weight: 400;\">. Inhalation provides the fastest symptom relief for medical cannabis patients due to how rapidly cannabis smoke and vapor are absorbed into the body. THC bioavailability is <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8803256\/#:~:text=At%20least%20100,to%2032%20hours.\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">up to 35%<\/span><\/a><span style=\"font-weight: 400;\"> for inhalation, while inhaled <\/span><a href=\"https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/full\/10.1111\/bcp.13710#:~:text=Absorption,%2C%2021.\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">CBD is around 31%<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Eating<\/strong>: Eating cannabis products such as\u00a0<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/edibles\/pros-cons\/\"><span style=\"font-weight: 400;\">edibles<\/span><\/a><span style=\"font-weight: 400;\">\u00a0(infused food and drinks) and capsules is also popular. It takes longer for the effects of the product to set in since it is processed through digestion and not absorbed directly into the bloodstream like it is when inhaled. <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8876728\/#sec2-pharmaceutics-14-00438:~:text=Systematic%20bioavailability%20data,routes%20%5B77%5D.\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Oral bioavailability ranges<\/span><\/a><span style=\"font-weight: 400;\"> from 10 to 20% for THC and 6 to 19% for CBD, notably lower than smoking.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\"><strong>Sublingual<\/strong>: Taking cannabis products such as\u00a0<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/how-to-make-a-cannabis-tincture-and-why-they-are-beneficial\/\"><span style=\"font-weight: 400;\">sublingual tinctures<\/span><\/a><span style=\"font-weight: 400;\">\u00a0can be an effective medicating method. Regarding bioavailability, sublingual intake of cannabinoids is somewhere between edible and inhalation because they utilize similar mucous membranes for absorption into the bloodstream. The onset is markedly faster than other oral methods of consumption.<\/span><\/li>\n<\/ul>\n<h2><b>What Are Cannabis Topicals and Why Do People Use Them?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Topical cannabis products are administered directly and absorbed through the skin. Topical products include transdermal patches, lotions, salves, creams, balms, and ointments. Different formulations of cannabis topical products may contain <\/span><a href=\"https:\/\/www.veriheal.com\/blog\/full-spectrum-vs-broad-spectrum-cbd\/\"><span style=\"font-weight: 400;\">different spectrums<\/span><\/a><span style=\"font-weight: 400;\">, or combinations of terpenes and cannabinoids naturally present in the cannabis plant.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The topical application of cannabis products involves rubbing or massaging the product directly onto the skin, usually where the user hopes to gain relief. Medical cannabis patients\u00a0may use topical products to <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8876728\/#:~:text=Table%203%20depicts,delivery%20of%20cannabinoids.\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">relieve muscle and joint pain<\/span><\/a><span style=\"font-weight: 400;\">, as well as various skin conditions, including eczema, psoriasis, and epidermolysis bullosa.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When it comes to topical cannabis products, they are not well absorbed into the rest of the body beyond the application site. This means they are not well \u201csystemically\u201d absorbed into the rest of the body, and won\u2019t cause a high even if THC is in the topical ointment. However, there aren\u2019t any human studies to estimate topicals\u2019 average bioavailability.<\/span><\/p>\n<h3><b>Can THC Be Absorbed Through the Skin?\u00a0<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">There are no human-based studies on the bioavailability of cannabinoids through a topical or transdermal application. However, preclinical<\/span> <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8876728\/#sec2-pharmaceutics-14-00438:~:text=Table%203.,delivery%20of%20cannabinoids.\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">animal studies<\/span><\/a><span style=\"font-weight: 400;\"> are promising.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">These application methods avoid a first-pass metabolism effect and provide local relief without entering the bloodstream since they are absorbed through the skin directly to dermal cannabinoid, pain, and anti-inflammatory receptors. Because of this limited but current information at hand, topical THC is not likely to cause a high due to negligible systemic absorption.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">A topical dilemma scientists are working on is that we know cannabinoids like CBD could use extra help getting through the skin. That\u2019s why <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8876728\/#sec2-pharmaceutics-14-00438:~:text=On%20the%20other%20hand%2C%20some,barrier%20%5B97%2C98%5D.\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">new topical formulations<\/span><\/a><span style=\"font-weight: 400;\"> including microemulsions and nanotechnology are being developed to enhance the delivery of cannabinoids into the deeper layers of the skin.<\/span><\/p>\n<h2><b>Can\u00a0THC<\/b><span style=\"font-weight: 400;\">\u00a0<\/span><b>Topicals\u00a0Show Up on a\u00a0Drug Test?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">If you\u2019re worried about THC topicals appearing on drug tests, we have good news!\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28122323\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">According to the available research<\/span><\/a><span style=\"font-weight: 400;\">, the topical application of THC products cannot lead to a positive cannabinoid finding in blood or urine.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Of course, these results cannot be guaranteed for everyone since they are not available on a massive scale, but they are promising so far.<\/span><\/p>\n<h2><b>Final Thoughts<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">While research on the bioavailability of cannabinoids through topical and transdermal application is still sparse, existing information suggests that THC and CBD topicals can potentially provide relief for localized pain and skin conditions without putting the user at risk of failing a drug test.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Are you interested in using cannabis topicals to treat a condition?\u00a0<\/span><a href=\"https:\/\/www.veriheal.com\/find-a-medical-marijuana-doctor\/\"><span style=\"font-weight: 400;\">Talk to an MMJ doctor today<\/span><\/a><span style=\"font-weight: 400;\">\u00a0to determine if medical cannabis is right for you.<\/span><\/p>\n<h2><b>Frequently Asked Questions<\/b><\/h2>\n<h3><b>How long does it take for THC topicals to work?<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Generally, it is expected that the effects of a topical will be felt within 10-30 minutes of application. Levels may peak around 1.4 hours and may be sustained for 48\u201372 hours depending on the exact application type.<\/span><\/p>\n<h3><b>Is THC topical better than CBD?<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Whether THC or CBD topicals are best for you depends on the legal status of both where you live and what kind of relief you are looking for. However, when it comes to bioavailability through the skin, more research needs to be done to ascertain the efficacy of THC topicals, whereas CBD topicals are more frequently applied for being widely and legally available for alleviating things like muscle pain.\u00a0<\/span><\/p>\n<h3><b>Will my CBD or THC-based option show up on a drug test?<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">According to available research, it has been indicated that THC topical cannabis products don\u2019t lead to a positive cannabinoid finding in blood or urine. However, there isn\u2019t a large enough data set to be 100% sure yet for everyone.<\/span><\/p>\n<h3><b>How do topical cannabis products work?<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Topical cannabis products provide local relief without entering the main bloodstream since they are absorbed through the skin directly. They act on dermal cannabinoids, pain, and other sensory and anti-inflammatory receptors.<\/span><\/p>\n<p><em>This article was first published in March 2023 by Olivia Swann and updated in November 2024.\u00a0<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>For those who suffer from muscle pain, chronic pain, or joint pain, cannabis topicals can be a game-changer &#8212; but how exactly do they work?\u00a0 Let\u2019s explore whether it\u2019s possible for THC in any of its forms to be absorbed through the skin, and if THC topicals can be detected on\u00a0drug tests. Top Ways to&#8230;<\/p>\n","protected":false},"author":84,"featured_media":37297,"parent":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[259],"tags":[13723,13724,13721,9019,4791,13725,13722,13720],"class_list":["post-26383","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","tag-bioavailability","tag-bioavailability-of-thc","tag-cannabis-topicals","tag-drug-tests","tag-joint-pain","tag-muscle-pain","tag-thc-absorbed-through-skin","tag-thc-topicals"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.1 (Yoast SEO v26.1.1) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Does Thc Absorb Through the Skin? What You Should Know<\/title>\n<meta name=\"description\" content=\"Can THC be absorbed through the skin? 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