{"id":26788,"date":"2024-05-07T08:00:59","date_gmt":"2024-05-07T12:00:59","guid":{"rendered":"https:\/\/www.veriheal.com\/blog\/?p=26788"},"modified":"2025-03-14T15:45:19","modified_gmt":"2025-03-14T19:45:19","slug":"combining-caffeine-and-thc","status":"publish","type":"post","link":"https:\/\/www.veriheal.com\/blog\/combining-caffeine-and-thc\/","title":{"rendered":"Combining Caffeine and THC: Benefits, Downsides, and Effects"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">It\u2019s likely you\u2019ve heard the term<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/discovering-the-wake-bake\/\" target=\"_blank\" rel=\"noopener\"> <span style=\"font-weight: 400;\">&#8220;wake and bake,&#8221;<\/span><\/a><span style=\"font-weight: 400;\"> as it is a very common phrase and practice among cannabis consumers and patients alike. Waking and baking is the act of consuming cannabis after waking up in the morning, most often in conjunction with a cup of coffee. Have you ever wondered about the effects of consuming coffee along with THC-rich cannabis? If so, you are in the right place\u2014we are going to explore the potential benefits and downsides of combining cannabinoids and caffeine.<\/span><\/p>\n<h2><b>Caffeine vs. THC in the Mornings<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">It is undeniable that coffee and cannabis can both result in euphoria. This is because both of these substances increase the brain&#8217;s levels of dopamine, aka the happiness hormone. There are many differences between THC and caffeine, but both serve a great purpose when consumed with intention shortly after waking up. While they are both quite different, there are reasons why individuals would choose to embrace one over the other in the mornings as well as many reasons why they should and often are consumed together.<\/span><\/p>\n<h3><b>Caffeine<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Caffeine, like coffee and energy drinks, is a go-to for many people on a daily basis, as it helps to boost your energy and improve your energy levels throughout the day. Caffeine is a stimulant that interferes with adenosine, a neurotransmitter. Adenosine levels typically surge throughout the day, inducing drowsiness. By obstructing adenosine receptors, caffeine boosts the function of alternative neurotransmitters like dopamine and norepinephrine, heightening alertness, focus, and vigor. Additionally, caffeine elevates acetylcholine release, which is linked to memory and learning, while diminishing GABA release, which is known for its inhibitory and relaxing effects.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, enjoying your first cup of java directly after waking up might not lead to the greatest benefits. It is suggested that since cortisol levels are the highest upon waking up, it may be best to wait at least one hour before indulging to get the most out of the effects of caffeine. This may also help you to avoid any unintentional tolerances to caffeine or interruption to your body\u2019s natural biological rhythm. There are other natural sources of caffeine aside from coffee as well that can be explored, such as kola nuts, green tea, and guarana.<\/span><\/p>\n<p><b>Potential benefits of caffeine in the morning:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Boost of energy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Better energy throughout the day<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased concentration<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased alertness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.hopkinsmedicine.org\/health\/wellness-and-prevention\/9-reasons-why-the-right-amount-of-coffee-is-good-for-you\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Decreased risk of Parkinson\u2019s and Alzheimer\u2019s disease<\/span><\/a><\/li>\n<\/ul>\n<h3><b>THC<\/b><\/h3>\n<p><a href=\"https:\/\/www.veriheal.com\/blog\/uncovering-thc-the-cannabis-plants-most-famous-cannabinoid\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">THC<\/span><\/a><span style=\"font-weight: 400;\">, which is short for delta-9-tetrahydrocannabinol, offers many potential therapeutic benefits\u2014so what better time to consume it than in the morning? While some strains of cannabis may make you sleepy, others can do just the opposite and give you a zap of energy to start off your day. Interestingly enough, <\/span><a href=\"https:\/\/www.veriheal.com\/blog\/will-cannabis-help-treat-chronic-fatigue-syndrome\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">one study<\/span><\/a><span style=\"font-weight: 400;\"> found that cannabis consumption was related to decreased symptoms in patients with chronic fatigue syndrome.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Check out these articles for good wake-and-bake strains:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.veriheal.com\/blog\/strains\/productivity\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">13 Best Cannabis Strains for High Energy and Productivity<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.veriheal.com\/blog\/strains\/daytime\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">9 Best Daytime Cannabis Strains<\/span><\/a><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">THC is often embraced for things such as depression, anxiety, PTSD, chronic pain, cancer-related pain, and nausea. When you live with conditions and symptoms such as these, consuming THC first thing can sometimes mean the difference between being able to face the day or having to surrender back to your bed\u2014or the doctor\u2019s office.<\/span><\/p>\n<p><b>Potential benefits of THC in the morning:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fights fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Decreased pain, anxiety, stress, nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased focus and productivity<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased patience<\/span><\/li>\n<\/ul>\n<h2><b>Effects of Mixing Caffeine and THC<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Mixing cannabis and caffeine may result in increased stimulating effects, depending on the amount of caffeine used to alter the effects of cannabis. Combining caffeine and edibles with a high THC content may not be the best choice, as edibles<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/fast-acting-edibles-are-changing-the-game-during-the-pandemic\/\" target=\"_blank\" rel=\"noopener\"> <span style=\"font-weight: 400;\">take some time to take effect<\/span><\/a><span style=\"font-weight: 400;\">. Nonetheless, there are some benefits to combining cannabis products and caffeine\u2014and it\u2019s not that hard to accomplish all of this in a single cup of coffee!<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Have you ever wondered if it&#8217;s possible to infuse your coffee with cannabis? The answer is: absolutely! There are many ways to do this, including adding THC-infused creamer, THC-infused sugar, or a basic<\/span> <a href=\"https:\/\/www.veriheal.com\/blog\/how-to-make-a-cannabis-tincture-and-why-they-are-beneficial\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">tincture<\/span><\/a><span style=\"font-weight: 400;\"> to your cup. Do you like to add butter to your coffee? Swap it for<\/span> <a href=\"https:\/\/www.veriheal.com\/blog\/how-to-make-cannabutter\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">cannabutter<\/span><\/a><span style=\"font-weight: 400;\">! Are you more of a latte person? Check out<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/edibles\/cannabis-infused-pumpkin-spice-latte-recipe\/\" target=\"_blank\" rel=\"noopener\"> <span style=\"font-weight: 400;\">this recipe<\/span><\/a><span style=\"font-weight: 400;\"> for a homemade cannabis-infused pumpkin spice latte (simply skip the syrup for an unsweetened latte!). If you&#8217;d rather skip the kitchen mess entirely, there are now some coffee products on the market that contain THC.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Of course, there are other ways of consuming THC or CBD along with caffeine that don\u2019t involve infusing coffee. You can choose to smoke or vape cannabis and sip on a cup of green tea, or perhaps you may prefer to take a sublingual tincture followed by a guarana soda. Whatever way you prefer to consume them, there are some benefits as well as some potential risks in the combination of caffeine and weed.<\/span><\/p>\n<p><b>Potential positive effects:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased dopamine:<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5448447\/#:~:text=Dopamine%20is%20basically%20associated%20with,dopamine%20in%20the%20brain%20(Fig.\" target=\"_blank\" rel=\"noopener\"> <span style=\"font-weight: 400;\">Cannabis and caffeine have both been shown<\/span><\/a><span style=\"font-weight: 400;\"> to increase dopamine levels, which in turn leads to increased happiness.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased levels of alertness and productivity have been linked to both THC and caffeine.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">THC and caffeine both help to fight fatigue, a fact that is backed by abundant research and anecdotal studies.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\"><br \/>\n<\/span><b>Potential negative side effects:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased heart rate or blood pressure: Cannabis and coffee are known to cause tachycardia, which is an<\/span><a href=\"https:\/\/www.acc.org\/latest-in-cardiology\/articles\/2016\/09\/22\/08\/58\/marijuana-and-coronary-heart-disease\" target=\"_blank\" rel=\"noopener\"> <span style=\"font-weight: 400;\">increased heart rate<\/span><\/a><span style=\"font-weight: 400;\">. If you have any underlying heart problems or problems with heart arrhythmias, consuming either separately or alone can cause heart complications.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Memory loss: Caffeine from coffee may<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3423236\/\" target=\"_blank\" rel=\"noopener\"> <span style=\"font-weight: 400;\">increase the short-term memory loss often associated with cannabis<\/span><\/a><span style=\"font-weight: 400;\">. It seems logical that the caffeine would counteract this cannabis effect since coffee can make you more alert, but caffeine and low doses of cannabis seem to impair cognitive function more than cannabis would on its own.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\"><br \/>\n<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/cannabis-cafes-are-beginning-to-open-up-across-the-world\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Cannabis cafes<\/span><\/a><span style=\"font-weight: 400;\">\u2014places where customers consume coffee and cannabis\u2014are opening up around the world in abundance and are being embraced by cannabis consumers. There are many reasons why people choose cannabis and caffeine, and as more research is performed, it seems that there are also significant benefits to consuming the two together. Check out the powers of caffeine and cannabis for yourself, and let us know what you think in the comments!<\/span><\/p>\n<hr \/>\n<p><i>Note: The content on this page is for informational purposes only and is not intended to be professional medical advice. Do not attempt to self-diagnose or prescribe treatment based on the information provided. Always consult a physician before making any decision on the treatment of a medical condition.<\/i><\/p>\n<h2><b>Sources<\/b><\/h2>\n<ol>\n<li style=\"list-style-type: none;\">\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bloomfield, M. A., Ashok, A. H., Volkow, N. D., &amp; Howes, O. D. (2016). The effects of \u03949-tetrahydrocannabinol on the dopamine system. Nature, 539(7629), 369\u2013377.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lee, L. K., &amp; Mhd Rodzi, N. A. R. (2022). Addressing the Neuroprotective Actions of Coffee in Parkinson&#8217;s Disease: An Emerging Nutrigenomic Analysis. Antioxidants (Basel, Switzerland), 11(8), 1587.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Leung, J., Chan, G., Stjepanovi\u0107, D., Chung, J. Y. C., Hall, W., &amp; Hammond, D. (2022). Prevalence and self-reported reasons of cannabis use for medical purposes in USA and Canada. Psychopharmacology, 239(5), 1509\u20131519.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Li, X., Diviant, J. P., Stith, S. S., Brockelman, F., Keeling, K., Hall, B., &amp; Vigil, J. M. (2022). The Effects of Consuming Cannabis Flower for Treatment of Fatigue. Medical cannabis and cannabinoids, 5(1), 76\u201384.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">NIDA. 2021, April 13. What are marijuana\u2019s effects on other aspects of physical health?. Retrieved from<\/span><a href=\"https:\/\/www.veriheal.com\/blog\/discovering-the-wake-bake\/\"> <span style=\"font-weight: 400;\">https:\/\/nida.nih.gov\/publications\/research-reports\/marijuana\/what-are-marijuanas-effects-on-other-aspects-of-physical-health<\/span><\/a><span style=\"font-weight: 400;\"> on 2024, April 5<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Panlilio, L. V., Ferr\u00e9, S., Yasar, S., Thorndike, E. B., Schindler, C. W., &amp; Goldberg, S. R. (2012). Combined effects of THC and caffeine on working memory in rats. British journal of pharmacology, 165(8), 2529\u20132538.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ren, X., &amp; Chen, J. F. (2020). Caffeine and Parkinson&#8217;s Disease: Multiple Benefits and Emerging Mechanisms. Frontiers in neuroscience, 14, 602697.Eskelinen, M. H., &amp; Kivipelto, M. (2010). Caffeine as a protective factor in dementia and Alzheimer&#8217;s disease. Journal of Alzheimer&#8217;s disease : JAD, 20 Suppl 1, S167\u2013S174.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Saraiva, S. M., Jacinto, T. A., Gon\u00e7alves, A. C., Gaspar, D., &amp; Silva, L. R. (2023). Overview of Caffeine Effects on Human Health and Emerging Delivery Strategies. Pharmaceuticals (Basel, Switzerland), 16(8), 1067.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sarshin, A., Naderi, A., da Cruz, C. J. G., Feizolahi, F., Forbes, S. C., Candow, D. G., Mohammadgholian, E., Amiri, M., Jafari, N., Rahimi, A., Alijani, E., &amp; Earnest, C. P. (2020). The effects of varying doses of caffeine on cardiac parasympathetic reactivation following an acute bout of anaerobic exercise in recreational athletes. Journal of the International Society of Sports Nutrition, 17(1), 44.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Turner AR, Patel P, Agrawal S. Marijuana. [Updated 2024 Feb 2]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Volkow, N. D., Wang, G. J., Logan, J., Alexoff, D., Fowler, J. S., Thanos, P. K., Wong, C., Casado, V., Ferre, S., &amp; Tomasi, D. (2015). Caffeine increases striatal dopamine D2\/D3 receptor availability in the human brain. Translational psychiatry, 5(4), e549.<\/span><\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<p><em>This article was originally published in April 2023 and most recently updated in May 2024.\u00a0<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>It\u2019s likely you\u2019ve heard the term &#8220;wake and bake,&#8221; as it is a very common phrase and practice among cannabis consumers and patients alike. Waking and baking is the act of consuming cannabis after waking up in the morning, most often in conjunction with a cup of coffee. Have you ever wondered about the effects&#8230;<\/p>\n","protected":false},"author":48,"featured_media":34809,"parent":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[254,259],"tags":[13776,13777,12483],"class_list":["post-26788","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lifestyle","category-research","tag-caffeine-and-cannabis","tag-caffeine-and-thc","tag-wake-and-bake"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.1 (Yoast SEO v26.1.1) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>What Happens When You Mix Caffeine and Marijuana?<\/title>\n<meta name=\"description\" content=\"The term &quot;wake and bake&quot; is a phrase that has spanned generations. Research now shows that caffeine and cannabis might be good for you! 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