{"id":37692,"date":"2025-01-16T08:00:10","date_gmt":"2025-01-16T13:00:10","guid":{"rendered":"https:\/\/www.veriheal.com\/blog\/?p=37692"},"modified":"2025-01-16T15:01:55","modified_gmt":"2025-01-16T20:01:55","slug":"is-it-safe-to-combine-weed-and-ambien","status":"publish","type":"post","link":"https:\/\/www.veriheal.com\/blog\/is-it-safe-to-combine-weed-and-ambien\/","title":{"rendered":"Is It Safe To Combine Weed And Ambien?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Cannabis and Ambien\u00ae (zolpidem) both boast some related effects and benefits, such as promoting relaxation and sleep. But although they may share similar outcomes, they are vastly different in nearly every other way.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Up to 30% of adults struggle with sleep disorders such as insomnia. Currently, the<\/span> <a href=\"https:\/\/www.thensf.org\/sleep-facts-and-statistics\/#:~:text=How%20Much%20Sleep,in%20their%20bedrooms.\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">National Sleep Foundation<\/span><\/a><span style=\"font-weight: 400;\"> recommends that adults ages 18-64 get between seven and nine hours of sleep. For seniors over the age of 65, seven to eight hours of sleep is recommended.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, over one-third of Americans aren\u2019t getting this recommended seven-hour minimum of sleep a night, which is <\/span><span style=\"font-weight: 400;\">why it comes as no surprise that people might consider combining the benefits of cannabis and Ambien to promote relaxation and a better night\u2019s sleep.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In this article, you\u2019ll gain a better understanding of how each of these substances affects the body when used individually or combined. <\/span><span style=\"font-weight: 400;\">After that, you can decide for yourself if the combination is your key to resting easy or too risky to consider.<\/span><\/p>\n<h2>What Is Ambien (Zolpidem) and What Are Its Uses?<\/h2>\n<p><span style=\"font-weight: 400;\">Ambien, which is the brand name for the drug known as zolpidem, is a popular medication typically used to treat insomnia by slowing down the brain and nervous system. <\/span><span style=\"font-weight: 400;\">It works by increasing GABA (gamma-aminobutyric acid) activity, which is a natural chemical in the brain. This chemical helps you relax, and in turn, makes it easier to sleep.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This drug helps people fall asleep faster and stay asleep better throughout the night. It\u2019s meant to be taken only when you are ready to go to bed because of its strong effects.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ambien is typically only used for a short period of time, and you shouldn\u2019t take it for more than a week without telling your doctor. Its dosing can also vary, particularly by biological gender, and some forms come in extended-release tablets.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some of the <\/span><a href=\"https:\/\/www.drugs.com\/ambien.html#:~:text=Ambien%20side%20effects,(more%20detail)\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">common side effects of Ambien<\/span><\/a><span style=\"font-weight: 400;\"> include headaches, drowsiness, daytime sleepiness, dizziness, tiredness, breathing problems (such as shallow breathing or shortness of breath), and gastrointestinal problems like nausea, constipation, upset stomach, or diarrhea.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">People can also experience abnormal thoughts or behaviors on Ambien. Some of these other side effects are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hallucinations, such as hearing or seeing things not there<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficulty concentrating<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Agitation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Muscle pain and discoordination<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Allergic reaction, possibly severe<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Worsening depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficulty concentrating<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Next-day or morning drowsiness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Performing activities while not fully awake and not remembering them the next day<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Short-term memory loss\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">However, other side effects can occur as well, depending on the person and their preexisting conditions or other concurrent medications. Alcohol and other sedative drugs shouldn\u2019t be taken with Ambien. You should report any unusual sleep activity or severe reactions right away, and always follow your prescriber\u2019s advice.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Importantly, Ambien is easily habit-forming or misused, and many patients have a hard time tapering off when they\u2019ve been on it for a while.\u00a0<\/span><\/p>\n<h2>How Cannabis Affects the Body When It Comes to Sleep<\/h2>\n<p><span style=\"font-weight: 400;\">After consuming cannabis, primary cannabinoids like THC and CBD interact with <\/span><a href=\"https:\/\/www.veriheal.com\/blog\/cannabinoids-and-the-endocannabinoid-system-a-match-made-in-heaven\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">our endocannabinoid system<\/span><\/a><span style=\"font-weight: 400;\">, influencing biological functions such as sleep.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The <\/span><a href=\"https:\/\/www.veriheal.com\/blog\/how-long-does-cannabis-high-last\/\"><span style=\"font-weight: 400;\">method of consumption<\/span><\/a><span style=\"font-weight: 400;\"> can also impact not only how quickly you feel the effects of cannabis, but also how long it affects your body. It\u2019s important to consider this when taking cannabis as a sleep aid or before combining it with another drug like Ambien.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For example, inhaling cannabis means a faster onset of the effects, but they may also wear off more quickly. The effects of smoking are typically more of a \u201chead buzz\u201d and peak within 30 to 60 minutes, tapering off within two to four hours. <\/span><span style=\"font-weight: 400;\">Edibles, however, take longer to affect you but might have a longer, more intense, lasting \u201cbody buzz\u201d effect because of how the body metabolizes the THC this way.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Certain<\/span> <a href=\"https:\/\/www.veriheal.com\/blog\/terpenes\/\"><span style=\"font-weight: 400;\">common terpenes<\/span><\/a><span style=\"font-weight: 400;\"> will also affect, and improve, sleep better than others. Many of these terpenes are classically found in Indica strains, which have a reputation for their relaxing, pain-relieving, and sedative-like properties.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some of the terpenes that can help with sleep and have other complementary benefits are:<\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400;\"> \u00a0 <\/span> <a href=\"https:\/\/www.veriheal.com\/blog\/terpenes\/myrcene\/\"><span style=\"font-weight: 400;\">Myrcene<\/span><\/a><span style=\"font-weight: 400;\">: Relieves inflammation, pain, and insomnia<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> \u00a0 <\/span> <a href=\"https:\/\/www.veriheal.com\/blog\/terpenes\/caryophyllene\/\"><span style=\"font-weight: 400;\">Caryophyllene<\/span><\/a><span style=\"font-weight: 400;\">: Relieves anxiety, depression, stress, inflammation, and pain<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> \u00a0 <\/span> <a href=\"https:\/\/www.veriheal.com\/blog\/terpenes\/limonene\/\"><span style=\"font-weight: 400;\">Limonene<\/span><\/a><span style=\"font-weight: 400;\">: Stress reducer, anti-depressant, and anxiety reducer<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> \u00a0 <\/span> <a href=\"https:\/\/www.veriheal.com\/blog\/terpenes\/linalool\/\"><span style=\"font-weight: 400;\">Linalool<\/span><\/a><span style=\"font-weight: 400;\">: Relieves anxiety, stress, inflammation, insomnia, and pain<\/span><\/li>\n<\/ul>\n<h2>Potential Interactions Between Ambien and Cannabis<span style=\"font-weight: 400;\">\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Certain effects of these two drugs can interact and increase in strength when taken together. Older adults especially are more susceptible to Ambien\u2019s effects since they often take more medications and have slower metabolisms.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">As zolpidem alone can have its own set of side effects, these may be exacerbated by cannabis and other drugs or result in new effects or side effects when combined.<\/span><\/p>\n<h3><b>Benefits:<\/b><\/h3>\n<ul>\n<li><b>Pairing Complementary Cannabis Strains: <\/b><span style=\"font-weight: 400;\">While Ambien can have some negative side effects, there are certain cannabis strains and terpenes that might help balance these out. For example, strains containing terpenes like caryophyllene and linalool can pair nicely with Ambien as they relieve depression, anxiety, and pain.<\/span><\/li>\n<li><b>Sleep Enhancement: <\/b><span style=\"font-weight: 400;\">Combining these two substances will how a powerful effect when it comes to falling asleep faster and staying asleep longer. Cannabis and hemp are also sometimes used anecdotally by people to taper off Ambien and switch to a more natural and less toxic way to fall asleep.<\/span><\/li>\n<\/ul>\n<h3><b>\u00a0<\/b><b>Risks:<\/b><\/h3>\n<ul>\n<li><b>Metabolization Issues:<\/b> <a href=\"https:\/\/bpb-us-e1.wpmucdn.com\/sites.psu.edu\/dist\/d\/117691\/files\/2020\/06\/Cannabinoid-as-PRECIPITANT-Medication-Affecting-the-Metabolism-of-ANOTHER-OBJECT-Medication_04_25.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Penn State<\/span><\/a><span style=\"font-weight: 400;\"> published a spreadsheet about how the body metabolizes Ambien and how cannabis consumption affects this metabolization. <\/span><a href=\"https:\/\/doh.dc.gov\/sites\/default\/files\/dc\/sites\/doh\/publication\/attachments\/Medical%20Cannabis%20Adverse%20Effects%20and%20Drug%20Interactions_0.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">CBD inhibits the CYP3A4 enzyme<\/span><\/a><span style=\"font-weight: 400;\">, which is the enzyme responsible for breaking down Ambien and many other medications. This means cannabis and zolpidem consumption together will increase the intensity and extend the effects of Ambien on the body.<\/span><\/li>\n<li><b>Dizziness: <\/b><span style=\"font-weight: 400;\">Combining these two drugs can cause excessive dizziness. Older adults should exercise caution to avoid falling, injuries, or accidents.<\/span><\/li>\n<li><b>Impaired Cognitive Function: <\/b><span style=\"font-weight: 400;\">Mixing Ambien and Cannabis may lead to confusion, which can be worse for the elderly. Impaired thinking, difficulty concentrating, and worsened judgment are similar side effects of this drug combination.<\/span><\/li>\n<li><b>Drowsiness: <\/b><span style=\"font-weight: 400;\">A feeling of excessive sedation can occur when mixing Ambien and cannabis. This could cause drowsiness even the next day, especially if taken late at night. This may be made worse depending on the strain of cannabis, such as Indica-heavy strains, or the type of Ambien, like the extended-release tablets.<\/span><\/li>\n<\/ul>\n<h2>Safety Considerations to Keep in Mind When Combining Ambien and Cannabis<\/h2>\n<p><span style=\"font-weight: 400;\">When combining these two drugs, certain activities should be avoided due to the side effects they create.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Driving or operating any heavy machinery, along with any activities that require mental alertness, are not recommended. Wait until you feel fully alert, awake, and sober to use your car.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The use of alcohol should be avoided when mixing Ambien and cannabis, or even when simply using one or the other. The combination of these two substances can cause new and additional side effects. You should ask your doctor before taking other sedatives, muscle relaxers, anticonvulsants, or narcotics (e.g., opioids, etc.).\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When mixing Ambien and cannabis for the first time, start with very low doses of each so you can see how your body responds. You might also consider a regular dose of one while <\/span><a href=\"https:\/\/www.veriheal.com\/blog\/microdosing-cannabis-explained-how-to-do-it-and-why-you-should-try-it\/\"><span style=\"font-weight: 400;\">microdosing with the other<\/span><\/a><span style=\"font-weight: 400;\"> to give just a slight added effect.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Consulting with your healthcare provider first is highly recommended, especially for those with a significant medical condition or those on other medications.<\/span><\/p>\n<h2>Alternatives to Ambien<\/h2>\n<p><span style=\"font-weight: 400;\">Since Ambien and cannabis have some strong effects when mixed, there are alternatives you can try instead. Using a more natural sleep aid as opposed to taking Ambien if you still plan to use cannabis is one option.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Many of the herbs listed below can also be<\/span> <a href=\"https:\/\/www.veriheal.com\/blog\/the-best-herbs-to-mix-with-cannabis\/\"><span style=\"font-weight: 400;\">mixed directly with cannabis<\/span><\/a><span style=\"font-weight: 400;\">\u00a0and have a wide range of possible benefits when smoked or otherwise consumed together.<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Valerian Root<\/b><span style=\"font-weight: 400;\">: Known for its calming effects, valerian root may help induce sleep and improve sleep quality.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Chamomile<\/b><span style=\"font-weight: 400;\">: Often consumed as a tea, chamomile boasts mild sedative and relaxation properties. Chamomile is high in the <\/span><a href=\"https:\/\/hashdash.com\/learn\/guides\/terpenes\/bisabolol\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">calming terpene bisabolol<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Lavender<\/b><span style=\"font-weight: 400;\">: You can use lavender via essential oil aromatherapy, or by consuming this herb to promote relaxation and a better night\u2019s sleep. Linalool is one of the main active ingredients responsible for these effects.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Melatonin<\/b><span style=\"font-weight: 400;\">: A natural hormone produced by the body that controls the sleep-wake cycle is called melatonin. It\u2019s often consumed in many forms, including pills, gummies, and liquids. Lower doses of melatonin tend to be more effective than higher doses.<\/span><\/li>\n<\/ul>\n<h2>Finals Takeaways<\/h2>\n<p><span style=\"font-weight: 400;\">Since Ambien and cannabis have such strong effects when used together, keep doses small and use extreme caution if you decide to combine them. <\/span><span style=\"font-weight: 400;\">Exploring alternative sleep aids to combine with cannabis might be a better method if you\u2019re concerned about negative side effects.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Be aware of the habit-forming and greater addictive nature of Ambien. Fortunately, cannabis may be an option to taper off it with fewer side effects if you experience physical dependence on zolpidem. If you are having trouble with chronic insomnia or are misusing Ambien, talk openly with your provider about ways to reduce or change your consumption.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cannabis and Ambien\u00ae (zolpidem) both boast some related effects and benefits, such as promoting relaxation and sleep. But although they may share similar outcomes, they are vastly different in nearly every other way.\u00a0 Up to 30% of adults struggle with sleep disorders such as insomnia. Currently, the National Sleep Foundation recommends that adults ages 18-64&#8230;<\/p>\n","protected":false},"author":84,"featured_media":37698,"parent":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[259],"tags":[17503,17507,17506,16018,17508,13665,7839,17451,17450,4188,17505,17504],"class_list":["post-37692","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","tag-ambien","tag-ambien-and-cannabis","tag-ambien-and-weed","tag-cannabis-for-sleep","tag-drug-combinations","tag-drug-interactions","tag-insomnia","tag-prescription-drugs","tag-prescription-medications","tag-sleep","tag-sleep-aids","tag-zolpidem"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.1 (Yoast SEO v26.1.1) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Ambien and Weed Together: Is It Safe?<\/title>\n<meta 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