{"id":39164,"date":"2025-07-28T06:00:24","date_gmt":"2025-07-28T10:00:24","guid":{"rendered":"https:\/\/www.veriheal.com\/blog\/?p=39164"},"modified":"2025-10-13T14:57:25","modified_gmt":"2025-10-13T18:57:25","slug":"research-reveals-cbds-potential-benefits-for-patients-with-glioma","status":"publish","type":"post","link":"https:\/\/www.veriheal.com\/blog\/research-reveals-cbds-potential-benefits-for-patients-with-glioma\/","title":{"rendered":"Research Reveals CBD’s Potential Benefits for Patients with Glioma"},"content":{"rendered":"

As research into the antitumor properties of cannabis compounds continues to expand, interesting evidence suggests that the activity of certain cannabinoids can help slow or reduce cancer cell growth to improve longevity and treatment effectiveness for patients with glioma. Gliomas are among the most aggressive, difficult-to-treat, and deadly brain tumors. Despite surgery, radiation, and chemotherapy, survival rates remain tragically low for these patients. E<\/span>merging research into <\/span>cannabidiol<\/span><\/a> (CBD) suggests that this non-intoxicating compound found in cannabis may offer novel therapeutic benefits in managing gliomas. A <\/span>2024 review<\/span><\/a> published in the <\/span>Journal of Translational Medicine<\/span><\/i> provides an overview of the growing body of evidence suggesting that CBD could play several meaningful roles in managing glioma, as well as aiding established treatment options.\u00a0<\/span><\/p>\n

According to the collected findings, this cannabis compound could <\/span>potentially improve<\/span><\/a> the lives of cancer patients with glioma by suppressing tumor growth, inflammation, and synergizing with chemo, and also by alleviating symptoms, like seizures and pain, that accompany the condition.\u00a0<\/span><\/p>\n

Generally, CBD, THC, and other cannabinoids may help <\/span>reduce treatment-related side effects<\/span><\/a> like nausea, poor appetite, and sleep, and protect organs from the <\/span>potentially toxic side effects<\/span><\/a> of chemo, radiation, and surgery. This article explores these emerging findings and further considers what such results might mean for the future of glioma care and the broader role of cannabis in cancer research and treatments.<\/span><\/p>\n

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What Is Glioma?<\/b><\/h2>\n

Glioma is a type of tumor that <\/span>originates in special supportive cells<\/span><\/a> found in the brain and spinal cord, called glial cells. These cells support nerve function with various tasks and are essential to the proper functioning of the nervous system. Patients with recurrent glioma face dire prognoses and limited treatment options.<\/span><\/p>\n

Gliomas make up about 50% of all malignant brain tumors, with the tumor\u2019s most aggressive form, called glioblastoma multiforme (GBM), accounting for nearly half of all primary malignant brain tumors in adults, and 70% of all gliomas. GBM is infamous for its overwhelmingly grave prognosis: the median survival time of patients after diagnosis is just 12\u201315 months, and the five-year survival rate hovers around 5%.<\/span><\/p>\n

Standard treatment includes surgery, radiation, and the chemotherapy drug temozolomide (TMZ). However, gliomas are often resistant to therapy due to their rapid growth, ability to evade the immune system, and resistance to drugs and radiation. For example, many patients don\u2019t respond well to TMZ, and the tumor often grows back following remission.\u00a0<\/span><\/p>\n

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CBD: An Overview<\/b><\/h2>\n

CBD is a natural chemical compound derived from the cannabis plant. Unlike the more famous cannabinoid, <\/span>tetrahydrocannabinol<\/span><\/a> (THC)\u2014the cannabinoid known for its intoxicating effects\u2014CBD is non-intoxicating, meaning it doesn\u2019t produce a \u201chigh.\u201d<\/span><\/p>\n

CBD nevertheless exerts its therapeutic effects via its unique interactions with the body\u2019s <\/span>endocannabinoid system<\/span><\/a> (ECS)\u2014a widespread cell-signaling network made up of cannabinoid receptors, internally produced cannabinoids (called endocannabinoids), and the enzymes used to break them down. The ECS plays a vital role in regulating a broad range of physiological functions, including those related to the nervous, cardiovascular, immune, and metabolic systems.\u00a0<\/span><\/p>\n

\"The<\/p>\n

CBD supports the endocannabinoid system by inhibiting the breakdown of endocannabinoids, thereby increasing their availability in the body. Additionally, CBD has <\/span>over 65 other important targets<\/span><\/a> in the body beyond the ECS. This extensive activity contributes to potential therapeutic benefits, such as:<\/span><\/p>\n