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News, Research

Is Cannabis Good for Bipolar Disorder? New Study Shows Cannabis Has ‘Unique Benefits’

Lemetria Whitehurst

by Lemetria Whitehurst

January 26, 2023 08:00 am ET Estimated Read Time: 5 Minutes
Is Cannabis Good for Bipolar Disorder? New Study Shows Cannabis Has ‘Unique Benefits’

Bipolar disorder is a complex condition that impacts millions worldwide, leading to extreme mood swings, intense emotional episodes, and difficulty managing day-to-day life. But there may be some good news for those coping with this mental health issue.

According to recent research, cannabis could offer unique benefits as part of an approach to managing bipolar disorder. In this article, we’ll explore how the potential advantages of cannabis might help stabilize symptoms associated with bipolar disorder. 

Bipolar Disorder Facts You Should Know

Statistics estimate that approximately 46 million people across the world live with bipolar disorder. Also called manic depression, bipolar disorder can affect relationships and work performance.

According to the National Institute of Mental Health, there are three types of bipolar disorder:

  • Bipolar I: characterized by episodes of manic behavior lasting at least a week and even requiring hospitalization
  • Bipolar II: characterized by alternating bouts of manic depression and depressive episodes, with increased agitation and energy 
  • Cyclothymic disorder: characterized by mood swings ranging from excessive energy to depression in an instant


Treatment for bipolar disorder typically involves psychotherapy and medication. Most commonly, pharmaceutical medication is prescribed to regulate moods. However, pharmaceutical medications can have side effects, and they may take longer to work for many patients.

Bipolar Disorder May Be Treatable With Cannabis, According to a New Study

New research shows that cannabis exhibits “uniquely beneficial effects” on cognitive performance and goal-directed behavior in bipolar patients. A team of researchers, who presented their study results during the Neuroscience 2022 conference, demonstrated that cannabis improves mental performance while reducing risky decision-making, a symptom commonly associated with bipolar disorder.

By reducing dopaminergic transmissions in the brain, cannabis may help suppress bipolar symptoms. Preliminary findings indicate that normalizing dopamine release can lead to improvements in goal-directed behaviors, suggesting beneficial effects on people suffering from BD. Further exploration of this possibility is underway to provide better care and more effective therapies for individuals living with the condition.

Using Cannabis for Bipolar Disorder Symptoms Is Also Supported by Early Research

Earlier groundbreaking research has also suggested cannabis consumption may be associated with improved bipolar disorder symptoms for patients. A 2016 experiment conducted by scientists from Harvard Medical School, Tufts University, and McLean Hospital explored the impact of marijuana on both mood and cognitive function in those diagnosed with this mental health condition, making it the first such study ever undertaken in this area. Initial findings showed no adverse effects on cognition due to cannabis use, further validating promising conclusions noted in previous studies regarding its potential beneficial properties when managing these disorders.

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Additionally, researchers discovered the plant’s potential to uplift moods, lessening depression and anger while increasing vigor. Surprisingly, it did not seem to have any notable impact on cognition when compared with subjects who abstained from marijuana intake.

Researchers concluded that marijuana could provide mood-stabilizing benefits to certain people living with bipolar disorder, as consuming cannabis appears to bring short-term alleviation of symptoms in such cases. Thus, this groundbreaking study laid the foundation for understanding how cannabinoids can support mental health.

Studies Show Cannabis Offers Particular Benefits to Patients With Depression and Low Mood

Bipolar disorder often goes unnoticed by people who don’t even realize they have it. However, they often tend to display mild mood swings as well as other symptoms of mood dysregulation. For these particular individuals on the other end of the bipolar spectrum, cannabis is also beneficial.

A 2020 study from the University of New Mexico recently unveiled promising results, showing cannabis flowers with high tetrahydrocannabinol (THC) levels may be a helpful remedy for reducing symptoms of depression. Researchers employed Releaf App data to uncover this remarkable correlation, suggesting that marijuana might play a role in treating certain mental health conditions. Jacob Miguel Vigil, a leading researcher involved in this study, noted that his team was particularly intrigued with how cannabis with high THC content levels showed immediate improvements in depressed feelings.

Furthermore, impressive advancements in medical research have demonstrated how cannabinoid-based products can positively impact our neurotransmission, neuroendocrine, and neuroimmune systems. In 2006 McGill University Health Center researchers discovered that administering the chemically synthesized URB579 agent had unprecedented results, producing “potent antidepressant-like effects” with animal models by preventing cannabinoids from degradation. According to the study’s lead author Gabriella Gobbi, for the first time ever, this study showed that drugs that increase brain levels of cannabinoids could improve mood. 

Furthermore, a 2020 study published in BMC Psychiatry revealed that whole-plant cannabis and plant-derived cannabinoids positively affect mood and sleep and reduce anxiety and psychotic symptoms.

As the depression epidemic rages on without any end in sight, a growing demand for natural solutions—safe and effective treatments that don’t come with harmful side effects like conventional antidepressants—is on the rise. Cannabis has proven to be just what many people need: an all-inclusive remedy sure to bring relief from mood disturbances so they can resume their everyday lives.

Final Thoughts

Though more research is needed before we can conclusively say that cannabis is an effective treatment for bipolar disorder, the years of research that have taken place thus far are promising. For those suffering from this condition and looking for an all-natural remedy, high-THC cannabis flower may be worth considering. Talk to a medical cannabis doctor to determine a good treatment plan for your symptoms.


Note: The content on this page is for informational purposes only and is not intended to be professional medical advice. Do not attempt to self-diagnose or prescribe treatment based on the information provided. Always consult a physician before making any decision on the treatment of a medical condition.

Post Your Comments

Canna grateful says:

January 30, 2023 at 10:28 pm

I am entirely grateful for having read this post and the concluding studies. My own personal struggle with depression and the effects Cannabis has on it are truly helpful I can’t say that it helps me not be absent-minded haha
but on the real, it helps me to live, laugh, and love
in and of itself – that is a wealth of health.

Reply
Bonnie Kathleen Hagood says:

February 12, 2023 at 11:32 am

Was born Bi-Polar, diagnosed officially at 11 years old, Took unhelpful pharmaceuticals for the next 50+ years. The most helpful thing in my life has been cannabis, which I started smoking in 1973. Still smoking, still taking pharmaceuticals, still bi-polar. My moods rocket around my brain like pinwheel fireworks. All day, Every day. When I get instantly upset pharma cant help much, and the pharmas take way too long to help with any immediate effects. Cannabis makes me feel instantly better.

Reply

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