Cannabis and CBD for Fibrous Dysplasia
Fibrous dysplasia is a benign (noncancerous) bone disease that results in distorted fibrous tissue instead of normal bone. As these areas of fibrous tissue grow and expand over time, they can weaken or distort the bone.
There are few or no symptoms in some patients with fibrous dysplasia. Most bones are damaged in other cases, however, and the disease is more severe. Such patients may need surgery to remove the damaged bone areas and to prevent or repair any fractures or deformities.
The consequence of a genetic mutation (change) on chromosome 20 is fibrous dysplasia. This mutation occurs in one gene that guides bone formation and development, but it remains unknown what causes this mutation. It is not genetic and is not considered to be caused by diet or aspects of the environment. Among males and females of all races, the mutation occurs similarly.
What is Fibrous Dysplasia
Fibrous dysplasia is a congenital, benign condition that causes the normal bone to be replaced by fibrous tissue and immature bone. Sometimes the abnormal growth is identified as scar-like lesions or benign tumors. The fibrous tissue is much softer than normal, healthy bone tissue. The irregular development causes bone weakness, which can increase the risk of fractures or distort the bone.
The monostotic type of fibrous dysplasia affects just one bone in the body. This is the most common form of the condition. The polyostotic version of fibrous dysplasia affects multiple bones but is less common.
Since symptoms vary in severity — the symptoms of some people are so mild that they don’t know they have the disease — it’s hard to understand how many people have fibrous dysplasia. Estimates suggest rates of one out of 15,000 people to one out of 30,000 have the disorder somewhere. It affects people of all races, and equally affects both men and women.
Fibrous dysplasia is rare, with only about 7% of all benign bone tumors. It can impact any bone in the body, but is most commonly found in the following:
- The femur (thighbone)
- Tibia (shinbone)
- Humerus (upper arm bone)
Fibrous dysplasia was associated with a gene mutation that causes an irregular form of fibrous bone to be produced by bone cells. Although the abnormal bone begins to form before birth, there is often no detection of its existence until infancy, adolescence or even adulthood.
The condition is generally divided into two types:
- Monostotic fibrous dysplasia— Only one bone will be affected. This is the condition’s most common form.
- Polyostotic fibrous dysplasia— It involves more than one bone. It may impact more than one bone throughout the body within the same limb or several bones. Usually, this form of the condition is more severe. Typically, it is found earlier in life for this reason.
Becoming malignant or cancerous is very rare in areas of fibrous dysplasia. It occurs in less than 1% of patients and is more likely to occur in patients with the condition’s polyostotic type or McCune-Albright syndrome.
Fibrous dysplasia is a chronic condition in which, instead of natural bone, scar-like tissue develops. It can affect any bone.
- Generally, fibrous dysplasia occurs in children between 3 and 15 years of age but is sometimes not diagnosed until adulthood.
- It is not known the exact cause of fibrous dysplasia, but it is not spread across families.
- Bone pain and deformity, waddling, and scoliosis may be symptoms.
- Care, medication, pain management, or physical therapy may be included in treatment.
Symptoms of Fibrous Dysplasia
Fibrous dysplasia, particularly if the condition is mild, may cause few or no signs and symptoms. More extreme dysplasia of the fibrous can cause:
- Bone pain, usually a mild to moderate dull ache
- Bone deformity
- Bone fractures, particularly in the arms or legs
- The curvature of leg bones
Fibrous dysplasia may affect any bone in the body, but the bones that are most frequently affected are:
- Thighbone (femur)
- Shinbone (tibia)
- Upper arm bone (humerus)
Fibrous dysplasia can rarely be associated with a condition that affects the endocrine system’s hormone-producing glands. The following abnormalities may include:
- Very early puberty
- Overactive hormone production
- Light brown spots on the skin
Increased bone pain may also be associated with the regular menstrual cycle or pregnancy hormonal changes.
How Cannabis Can Help Relieve the Symptoms of Fibrous Dysplasia
Pain is a major concern for fibrous dysplasia patients. The pain in the bones can be a pain that throbs or radiates pain. Medical marijuana can provide immediate relief for patients with fibrous dysplasia for chronic pain control, achy muscles, and fatigue.
THC and CBD, two cannabinoids found in different varieties of marijuana medicine, help to reduce both acute and chronic pain. The cannabinoids activate receptors for CB1 and CB2 that can help manage pain levels. In some cases, fibrous dysplasia medical marijuana can treat pain that does not respond to conventional options for pain management.
Stiffness is another potential condition-related symptom. The stiffness may be helped by surgical procedures to treat the condition. Marijuana can help to reduce stiffness, making it easier to travel. Reduced pain and rigidity will mean a more normal life for patients.
For two primary reasons, research into marijuana and fibrous dysplasia is very minimal. Second, the illness is rare, so researchers like diseases with higher incidences are not drawn by it. Second, marijuana is considered a substance in Schedule 1, and researchers often have limited access to it, making it difficult for science.
Patients with fibrous dysplasia may find relief from pain through the use of cannabis, despite a lack of research. In addition to relieving pain, marijuana can help improve bone health and help to heal after fractures. Several cannabinoids, including CBD, CBC, and CBG, can stimulate bone growth as a result of fibrous dysplasia that can help patients with bone weakness.
Medical Cannabis Treatment for Fibrous Dysplasia
Scientific research on cannabis and fibrous dysplasia may be minimal, but you can find the right balance of relief from symptoms by doing your own experiment with different strains.
The marijuana strain that you use depends on the other results that you want. Sativa-dominant marijuana strains provide effective fibrous dysplasia pain relief. Such strains appear to have an aggressive effect as well. This is perfect if during the day you use medical marijuana and want to stay alert or have more control.
Often, Indica-dominant marijuana strains are useful in pain treatment. Such marijuana varieties appear to have a sedative effect that will help you sleep. Use these strains when your regular sleep cycle is disrupted by fibrous dysplasia pain. The combination of pain relief and sedation can help you fall asleep and stay asleep for longer without pain-related waking.
Once you have chosen a marijuana strain, you need to choose a cannabis intake method. The age of the patient is considered when selecting the method of ingestion. Most often, smoking is associated with drug use, but since fibrous dysplasia affects children predominantly, smoking is not a good option. Smoking is not always acceptable, even in older patients, as it can exacerbate asthma and lung problems.
Here are other ingestion options to consider when treating fibrous dysplasia with marijuana:
- Vaporizing: Vaping marijuana is an alternative to smoking with some benefits. Unlike smoking, vaping almost instantly induces the weed to take effect. This makes it a popular choice for pain relief immediately. You use a much lower heating point when vaporizing marijuana than smoking, which creates fewer by-products. This can make your breathing healthier.
- Edibles: Another way marijuana can be consumed is by edibles. The only choice is not pot-laced brownies. In a number of categories, you can find edibles flavored with marijuana, including gum, cookies, ice cream, desserts, blended snacks, and other items. It helps you to enjoy more variety and something that appeals to you. Edibles are required to work longer than vaporizing. Expect relief from 30 minutes to several hours after eating the food filled with cannabis. The effects of edible marijuana, however, last much longer than smoking or vaping once it kicks in.
- Topical application: Updated versions are an option if you want to add marijuana to a certain location. These come in various kinds, including salves, oils, and lotions. The topical marijuana products are applied directly to the pain source, which can help you get concentrated pain relief.
Medical marijuana helps many people find pain relief from conventional treatments for pain relief that they haven’t found. Because pain is the primary side effect of fibrous dysplasia can be an effective option for condition patients. If you or a loved one is suffering from fibrous dysplasia, medical marijuana could be an effective treatment option for the pain and stiffness you experience.
It can be extremely helpful for an experienced marijuana doctor to determine which varieties to use at different times. The doctor will examine your particular case and medical history to help you find the right options. Keep in mind that finding a good match for you sometimes takes some experimentation with different strains.