Your medical cannabis journey simplified: find partnered dispensaries, explore pricing options, earn rewards, and get answers to FAQs, all in one spot.
January 5, 2021 05:00 pm ETEstimated Read Time: 5 Minutes
Those of you who have had a migraine before will know that it is much more than pain. Cannabis has shown to have properties that can alleviate the symptoms of this disabling condition but now a study has shown that a single dose of psilocybin could provide long-lasting therapeutic benefits. Migraine treatments can often be unsuccessful so the fact that cannabis and psilocybin present as potentially effective treatments is quite important for those in need of relief. That being said, let’s have a look at the study which found the promise of psilocybin for long-lasting therapeutic benefits.
Psilocybin is Illegal but Research is in Progress
Psilocybin is the psychoactive compound found in certain mushrooms, which is also why these mushrooms are often referred to as “magic” mushrooms, shrooms, or even liberty caps. The substance is historically used as entheogens in ceremonies and spiritual practices. Psilocybin is still illegal throughout much of the world but fortunately, there is a rising force of support and increases in research in order to improve the chances of legalization.
If you would like to learn more about psilocybin and how one could combine the therapeutic potential of psilocybin and cannabis, be sure to check out this article.
Researching Psilocybin for Migraines
A team of researchers had their study published in Neurotherapeutics where they explored the migraine-suppressing effects of psilocybin. While psilocybin consumers can attest to the therapeutic effects of the substance, science has yet to support many of the claims.
This study is the first to make use of a double-blind, placebo-controlled, crossover design in order to assess the early feasibility of psilocybin for migraines (5). A double-blind study is when neither the participants nor the researchers know whether the placebo and actual substance is being administered to each participant. The placebo-controlled part of the study means that the researchers are using a substance with no effect as well as the actual substance in order to see if the psilocybin actually has an effect (3). The crossover part means the subjects were initially given a placebo and then transitioned to psilocybin.
Emmanuelle Schindler, the study’s first author, explained in an interview that “as a headache medicine physician, I see the need for a better understanding of headache disorders, including migraine, and the need for more treatment options. I’ve also studied the neuropharmacology of psychedelics for a number of years and appreciate their ability to help us understand more about the workings of the human brain (2).”
Schindler goes on to state that when she learned that “patients with certain headache disorders reported lasting improvements after just a single or few doses of psilocybin or other psychedelics.” This made her wonder “whether these drugs couldn’t help us better understand the underlying pathology in headache disorders, as well as serve as a new form of treatment (2).”
Apply For Your Medical Marijuana Card Today
Veriheal has satisfied hundreds of thousands of patients nationwide
Get approved or your money back
Appointments available on-demand
Customer support available 24/7
The study involved seven women and three men who frequently experienced migraines. The participants received a placebo at first, though no one knew this at the time (5). They then moved on to consuming low doses of psilocybin; both of which were capsules. The participants also maintained a diary to document their migraines and began doing so two weeks after the first capsule was administered and two weeks after the active dose of psilocybin.
The researchers found that psilocybin was associated with reductions in pain severity as well as improving the functional impairments commonly associated with migraines. Schindler told PsyPost that “This study is very preliminary and does not serve as a guide for how to manage migraine with psilocybin, but it does offer some important information (2).” During this interview, Schindler clarified that it was not a single episode of migraine that was being studied, but rather the disorder. She also explained that the doses of psilocybin were minimal and that the participants did not have any psychedelic experiences.
The participants only received psilocybin once during the study but had continued to provide relief similar to the effect of taking a daily preventive medication (5). Considering the small dose with long-lasting effects, the reduction in pain, and improvement in functioning, Schindler stated that “there is no other oral treatment that can do this (2).”
A different study by Schindler was published in 2015 and found that psilocybin was also effective against a disorder called cluster headache – which is significantly painful (6). In this study, Schindler explained that lower doses were not only used and effective but were also preferred by the patients who expressed a dislike for taking higher doses.
More Supporting Research is Needed
While small doses of psilocybin are reported to be effective with long-lasting therapeutic effects, there is much that still needs to be understood. This includes the likes of different doses and their safety when being consumed on a recurring basis as well as any potential variances amongst the magic mushroom strains, in case there is any significant factor.
Self-medicating with psychedelics can be dangerous which is why we recommend that you only treat yourself with psilocybin under the treatment plan of a professional. If you are in a location where you are allowed to consume psilocybin, consider doing so by microdosing. This is when you consume low doses more frequently (i.e daily). It is also important to remember that the jury is still out on many important aspects of using psilocybin as a treatment, despite the plenty of promising anecdotal reports.
Note: Veriheal does not support illegally consuming therapeutic substances like psilocybin magic mushrooms but acknowledges that it transpires because of the current illicit status, which we strive to change by advocating for research, legal access, and responsible consumption. Always consult a physician before attempting alternative therapies.
6. Schindler, E. A., Gottschalk, C. H., Weil, M. J., Shapiro, R. E., Wright, D. A., & Sewell, R. A. (2015). Indoleamine hallucinogens in cluster headache: Results of the Clusterbusters Medication Use Survey. Journal of Psychoactive Drugs, 47(5), 372–381. https://www.tandfonline.com/doi/abs/10.1080/02791072.2015.1107664
Chane Leigh, aka The Bud Fairy, is a South African cannabis advocate and enthusiast with a firey personality and a thirst for travel. She loves to educate people and to question the norms.
Have you ever become so involved with an activity that you forget about about everything else? Did this leave you feeling like you were completely present or “in the zone”? In positive psychology, such experiences characterize a state known as “flow.” Flow is a cognitive state where a person is completely immersed in an activity,…
Navigating the laws on traveling with medical marijuana (MMJ) is incredibly confusing with the current global stance on cannabis. In the U.S., some states are okay with you bringing your medicine with you as long as you can prove your patient status, while other states are staunchly against it altogether, leaving MMJ patients in a…
Cannabis edibles are a preferred method of consuming cannabis by both retail consumers and medical cannabis patients alike. But just how long do they last? Let’s explore the shelf life of edibles, how to store them, and what to do if they go bad. What Are Edibles? Common Types of Edibles How Long Do Edibles…
People have been smoking joints for a long time. The first rolling papers surfaced around the early 1500s in Alcoy, Spain. These weren’t like the rolling papers we know today though. To start, these papers were intended for tobacco, not cannabis. They were made of hemp along with other textiles and lacked an adhesive gum…
Just in time for the holidays, the Jet Lag strain brings a smoking experience completely different than what the name suggests. Jet Lag is an energizing sativa that settles into a creative, silly high. And for an anxious flower-lover like me, this strain was the first step in my journey to finding the perfect cannabis…
We use our own as well as third party cookies to improve your site experience and the services we make available. You can learn more about our use of cookies in our Privacy Policy.
6. Schindler, E. A., Gottschalk, C. H., Weil, M. J., Shapiro, R. E., Wright, D. A., & Sewell, R. A. (2015). Indoleamine hallucinogens in cluster headache: Results of the Clusterbusters Medication Use Survey. Journal of Psychoactive Drugs, 47(5), 372–381. https://www.tandfonline.com/doi/abs/10.1080/02791072.2015.1107664
Content Disclamer
The statements made regarding cannabis products on this website have not been evaluated by the Food and Drug Administration (FDA). Cannabis is not an FDA-approved substance and is still illegal under federal law. The information provided on this website is intended for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. It is not intended as medical advice and should not be considered as a substitute for advice from a healthcare professional. We strongly recommend that you consult with a physician or other qualified healthcare provider before using any cannabis products. The use of any information provided on this website is solely at your own risk.
6. Schindler, E. A., Gottschalk, C. H., Weil, M. J., Shapiro, R. E., Wright, D. A., & Sewell, R. A. (2015). Indoleamine hallucinogens in cluster headache: Results of the Clusterbusters Medication Use Survey. Journal of Psychoactive Drugs, 47(5), 372–381. https://www.tandfonline.com/doi/abs/10.1080/02791072.2015.1107664